Re2O

• Dull, thin or crepey skin that has lost firmness
• Those who want to support the skin’s structure, not only hydrate the surface
• Uneven texture or shallow depressed scars
• Anyone comparing next-generation boosters after trying other options

Suitability, treatment areas and the right number of sessions are confirmed during consultation.

• 01

  Where you are now, and where we start

  Skin showing dryness, rough texture and loss of elasticity together

• 02

  The change you want, the impression you keep

  Suitability, treatment areas and the right number of sessions are confirmed during consultation.

• 03

  How it differs from similar options

  These injectable skin boosters all support skin quality, but they use different materials and work in different ways, so they suit different goals.

• 04

  Health information and recovery schedule

  Little downtime; small raised bumps at the injection sites may appear and usually settle within about 2–3 days. Temporary redness, mild swelling, tenderness or minor bruising may occur. Avoid saunas, heat and intense exercise briefly, use sun protection, and follow the soothing guidance we provide.

Before the product name we match the actual ingredients, the injection layer and your skin concern, then decide the dose, the interval and anything done alongside it.

Re2O is often described as a fourth-generation, ECM-based booster. Rather than only prompting the skin to make new collagen, it delivers ready-made extracellular-matrix material — mainly collagen, with elastin, hyaluronic acid and other ECM components derived from human-tissue matrix — into the dermis, where it acts as a scaffold that supports dermal structure and remodeling over the following weeks. It is placed with fine microinjections across the treatment area. This differs from polynucleotide boosters such as Rejuran, which support the skin’s own repair, and from PDLLA boosters such as Juvelook, which prompt collagen renewal.

How it works

• 01

  Ready-made matrix, not just a signal

  Rather than only prompting the skin to make new collagen, Re2O delivers extracellular-matrix material — mainly collagen, with elastin and hyaluronic acid — directly into the dermis.

• 02

  A scaffold in the dermis

  The ECM components act as a supportive scaffold within the dermis, where the skin’s own cells can organize and remodel over the following weeks.

• 03

  Placed with fine microinjections

  Fine microinjections distribute the material evenly across the treatment area, at the depth chosen for your skin.

• 04

  Why change is gradual

  Because remodeling follows the skin’s own timeline, firmness and texture develop over weeks rather than immediately. (Results vary by individual.)

1. 01

   Ingredients and authenticity

   Consultation and skin assessment

2. 02

   Anatomy and expression

   Cleansing and numbing cream

3. 03

   Small amounts, one stage at a time

   A typical plan is a short course of about 2–3 sessions spaced roughly 4–6 weeks apart, with changes developing gradually over about 4–8 weeks as the skin remodels. A maintenance session may be considered after a period decided at consultation. (Results vary by individual.)

What the procedure is like

• Little downtime; small raised bumps at the injection sites may appear and usually settle within about 2–3 days.
• Temporary redness, mild swelling, tenderness or minor bruising may occur.
• Avoid saunas, heat and intense exercise briefly, use sun protection, and follow the soothing guidance we provide.

Safety & considerations

Whether Re2O suits your skin is confirmed during consultation, and it is not suitable for everyone. Effects develop gradually and vary by individual, and side effects may occur.

1. DAY 0

   Treatment day

   Numbing first, then microinjections. Small raised bumps, mild redness or a flushed feeling may appear at the injection sites.

2. DAY 1-3

   Bumps settling

   The small bumps and any swelling usually soften and settle. Minor bruising, if any, begins to fade.

3. WEEK 1-4

   Early remodeling

   The skin begins to work with the delivered matrix. Changes at this stage are subtle and vary between people.

4. 4-8 WEEKS

   Skin-quality change

   As the dermis remodels, many people notice firmer, smoother-looking skin. This is typically when results are assessed. (Results vary by individual.)

5. AFTER THE COURSE

   Review & maintenance

   Your doctor reviews the outcome and discusses timing for any maintenance session based on your skin.

Neither is “better” — they work differently and suit different goals. The right choice is decided after we assess your skin.

• Q. How is Re2O different from Rejuran or Juvelook?

  The difference lies in what is placed into the skin. Re2O delivers the extracellular matrix components that form the skin's own scaffolding — collagen, elastin and hyaluronic acid — directly, so the underlying foundation is supported. In Rejuran the lead ingredient is PN, which stimulates regeneration, and in Juvelook it is PDLLA, which prompts the skin to build collagen. Put simply, one supplies the material and the other asks the skin to make it.

• Q. Will one session alone make a difference?

  Some people notice more hydration and a smoother texture after a single session, but we usually plan several sessions as one course. The components that have been placed need time to settle, and the skin needs time to respond. How many sessions you have, and how far apart, is decided after looking at the condition of your skin and what you want to achieve.

• Q. How long do the injection marks and swelling last?

  Small marks and mild swelling appear where the injections were placed, and they usually settle within one to three days. Some people bruise, so if you have an important occasion coming up it is better to allow about a week. On the day of the treatment, please avoid saunas, strenuous exercise and alcohol.

• Q. Can it only be done on the face?

  We also use it on areas where the skin is thin and the texture is a concern, such as the neck and the backs of the hands. Skin thickness and recovery speed differ from one area to another, though, so we set the amount injected and the depth differently. Which areas to treat is something we decide together at the consultation, after examining your skin.

• Q. I am worried about allergies — is there anything I should check beforehand?

  Before the treatment we go through the ingredients in the product alongside any allergies you have had. If you have ever reacted to a particular protein or to an anesthetic, please be sure to tell us. If you are being treated for an autoimmune condition or taking anticoagulants, please let us know in advance as well, so that we can adjust the amount injected and the timing.

• Q. How do I choose a clinic for Re2O in Gangnam, Seoul?

  Look at the examination and the plan rather than the treatment name. First, what the clinic checks before deciding — at QD Clinic in Gangnam, Seoul, the first thing we look at for this treatment is “Skin showing dryness, rough texture and loss of elasticity together”. Second, whether it explains why it recommends that scope and method, compared with the alternatives. Third, whether it reviews your progress with you when results are expected. Our doctor goes through these three points at consultation before the treatment is decided.

• Q. Where can I get Re2O in Seoul?

  At QD Clinic in Gangnam, Seoul, South Korea. We are at 3F, 502 Gangnam-daero, Gangnam-gu, Seoul (Nonhyeon-dong, Seohee Building), a 4-minute walk from Exit 3 of Nonhyeon or Sinnonhyeon Station. Call +82-2-514-1650 or use the consultation form on this site to book a doctor’s consultation first.